骨髓间充质干细胞用于胶质瘤治疗的相关研究进展
吴登科,黄红星 吴登科、黄红星,长沙,湖南省脑科医院神经外科,410001
摘要: Friedenstein等1970年报道,培养骨髓细胞时,发现一种呈克隆生长的成纤维样细胞,它能产生成纤维细胞集落形成单位(CFU-F),在一定条件下可分化为成骨细胞、成软骨细胞、脂肪细胞、成肌细胞。Caplan [1] 将这种具有多向分化能力的成纤维样细胞定义为骨髓间充质干细胞(bone marrow-derived mesenchymal stem cells,MSCs)。有实验发现神经干细胞具有向胶质瘤所在区域游走及聚集的潜能,并提出这种趋向性游走有可能用于胶质瘤基..
文献标引:吴登科,黄红星.骨髓间充质干细胞用于胶质瘤治疗的相关研究进展.中华临床医师杂志(电子版),2008,2(3):346-350.
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