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药代学药效学和围术期循环功能调控
张马忠,杭燕南,王祥瑞
张马忠、杭燕南、王祥瑞,上海交通大学医学院附属仁济医院麻醉科,200001

摘要:  几乎没有一种麻醉药能单独用于临床手术麻醉,尤其对那些高风险非心脏手术患者。为获得满意的麻醉效果、保持血流动力学稳定、减少心肌缺血等不良反应的发生,麻醉药选择主要基于围术期心室功能、是否需早期拔管、医生对药代学/药效学和药物相互作用的了解及使用经验等加以综合考虑。   一、麻醉药对心血管功能的影响 [1-3]   1. 异丙酚:可扩张血管、降低全身血管压力和抑制心肌收缩性,抑制或重新设定压力反射,..

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文献标引:张马忠,杭燕南,王祥瑞.药代学药效学和围术期循环功能调控.中华临床医师杂志(电子版),2008,2(3):332-339.  

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