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Graves眼病免疫治疗的新靶点

王坚

王坚,南京军区南京总医院内分泌科,210002

关键词:Graves眼病; 治疗,新靶点

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文献标引:王坚.Graves眼病免疫治疗的新靶点[J/CD].中华临床医师杂志:电子版,2010,4(1):1-3.

参考文献:
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[2] Valyasevi RW,Harteneck DA,Dutton CM,et al. Stimulation of adipogenesis,peroxisome proliferator-activated receptor-gamma(PPARgamma),and thyrotropin receptor by PPARgamma agonist in human orbital preadipocyte fibroblasts. J Clin Endocrinol Metab,2002,87(5):2352-2358.[PubMed]
[3] Zhang L,Baker G,Janus D,et al. Biological effects of thyrotropin receptor activation on human orbital preadipocytes. Invest Ophthalmol Vis Sci,2006,47(12):5197-5203.[PubMed]
[4] Kumar S,Coenen MJ,Scherer PE,et al. Evidence for enhanced adipogenesis in the orbits of patients with Graves′ ophthalmopathy. J Clin Endocrinol Metab,2004,89(2):930-935.[PubMed]
[5] Pritchard J,Han R,Horst N,et al. Immunoglobulin activation of T cell chemoattractant expression in fibroblasts from patients with Graves′ disease is mediated through the insulin-like growth factor I receptor pathway. J Immunol,2003,170(12):6348-6354.[PubMed]
[6] Kremer JM,Westhovens R,Leon M,et al. Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med,2003,349(20):1907-1915.[PubMed]
[7] El Fassi D,Nielsen CH,Bonnema SJ,et al. B lymphocyte depletion with the monoclonal antibody rituximab in Graves′ disease:a controlled pilot study. J Clin Endocrinol Metab,2007,92(5):1769-1772.[PubMed]
[8] Bonara P,Vannucchi G,Campi I,et al. Rituximab induces distinct intraorbital and intrathyroidal effects in one patient satisfactorily treated for Graves′ ophthalmopathy. Clin Rev Allergy Immunol,2008,34(1):118-123.[PubMed]
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[11] Finamor FE,Martins JR,Nakanami D,et al. Pentoxifylline(PTX)-an alternative treatment in Graves′ ophthalmopathy(inactive phase):assessment by a disease specific quality of life questionnaire and by exophthalmometry in a prospective randomized trial. Eur J Ophthalmol,2004,14(4):277-283.[PubMed]
[12] Pritchard J,Horst N,Cruikshank W,et al. Igs from patients with Graves disease induce the expression of T cell chemoattractants in their fibroblasts. J Immunol,2002,168(2):942-950.[PubMed]
[13] Aguirre-Balsalobre F,Mengual-Verdú E,Muñoz-Acosta JM,et al. Octreotide scintigraphy in thyroid orbi-topathy gammagrafia con ocireotido en la orbitopatia distiroidea(in English). Arch Soc Esp Oftalmol,2007,82(3):133-139.[PubMed]
[14] Dorkhan M,Lantz M,Frid A,et al. Treatment with a thiazolidinedione increases eye protrusion in a subgroup of patients with type 2 diabetes. Clin Endocrinol(Oxf),2006,65(1):35-39.[PubMed]
[15] Lee S,Tsirbas A,Goldberg RA,et al. Thiazolidinediones induced thyroid associated orbitopathy. BMC Ophthalmol,2007,7:8.[PubMed]
[16] Starkey K,Heufelder A,Baker G,et al. Peroxisome proliferator-activated receptor-gamma in thyroid eye disease:contraindication for thiazolidinedione use?J Clin Endocrinol Metab,2003,88(1):55-59.[PubMed]
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